median eminence การใช้

• CRH and vasopressin are released from neurosecretory nerve terminals at the median eminence.
• The median eminence is only occasionally included as part of the posterior pituitary.
• Other hormones secreted from the median eminence include vasopressin, oxytocin, and neurotensin.
• The tanycytes of the median eminence are often found along the fenestrated peripheral capillaries.
• The median eminence is rich in fenestrated capillaries, allowing for the passage of proteins and neurohormones.
• The major cell type that makes up the median eminence are specialized ependymal cells known as tanycytes.
• The median eminence is one of the seven areas of the brain devoid of a blood brain barrier.
• They are tightly packed on the capillaries, forming a seal between the third ventricle and the median eminence.
• More specifically, the median eminence allows for the transport of neurohormones between the CSF and the peripheral blood supply.
• The hypothalamus produces releasing hormones and neurohypophysial hormones in specialized hypothalamic neurons which extend to the median eminence and posterior pituitary.
• These two neuronal systems project axons to the median eminence, where they release their peptides into portal blood vessels for transport to the anterior pituitary.
• The "'median eminence "'( ME ) is located in the inferior portion of the hypothalamus and is ventral to the third ventricle.
• This seal can be attributed to the tight junctions observed between tanycytes and functions to restrict the travel of molecules between the median eminence and the third ventricle.
• Following secretion, TRH travels across the median eminence to the anterior pituitary gland via the hypophyseal portal system where it stimulates the release of thyroid-stimulating hormone from cells called thyrotropes.
• Some of these factors ( releasing hormones ), released at the hypothalamic median eminence, control the secretion of pituitary hormones, while others ( the hormones oxytocin and vasopressin ) are released directly into the blood.
• Vasopressin and oxytocin are also synthesized in the parvocellular neurosecretory cells of the paraventricular nucleus of the hypothalamus, which project to the median eminence, where they are transported and secreted into the hypophyseal portal system to stimulate the anterior pituitary.
• The "'arcuate nucleus "'of the hypothalamus ( also known as ARH, ARC, or infundibular nucleus ) is an aggregation of neurons in the mediobasal hypothalamus, adjacent to the third ventricle and the median eminence.
• Findings have suggested that thyroid hormone ( T4 ) is taken up by the hypothalamic glial cells in the infundibular nucleus / median eminence, and that it is here converted into MCT8, a thyroid hormone transporter, supporting the theory that T3 is transported into them.
• The hypothalamus controls the anterior pituitary gland via " releasing factors " and " release-inhibiting factors "; these are blood-borne substances [ author means via bloodstream and not by the lymphatic system nor air, nor any other modes of transport ] released by hypothalamic neurons into blood vessels at the base of the brain, at the median eminence.